Note: This document contains side effect information about bicalutamide. Some of the dosage forms listed on this page may not apply to the brand name Casodex.
Common side effects of Casodex include: abdominal pain, nausea, and mastalgia. Other side effects include: flu-like symptoms, gynecomastia, vomiting, and anorexia. See below for a comprehensive list of adverse effects.
Applies to bicalutamide: oral tablet
Along with its needed effects, bicalutamide (the active ingredient contained in Casodex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking bicalutamide:
Incidence not known
Some side effects of bicalutamide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Applies to bicalutamide: oral tablet
Very common (10% or more): Pain (35%), asthenia (22%), peripheral edema (13%)
Common (1% to 10%): Weight loss, weight gain, fever, chills, hernia, cyst
Very common (10% or more): Hot flashes (53%)
Common (1% to 10%): Chest pain, hypertension, angina pectoris, congestive heart failure, myocardial infarction, coronary arrest, coronary artery disorder, syncope
In patients with advanced prostate cancer treated with this drug in combination with an LHRH analog, the most frequent adverse reaction was hot flashes (53%).
Very common (10% or more): Constipation (22%), pelvic pain (21%), nausea (15%), diarrhea (12%), abdominal pain (11%)
Common (1% to 10%): Dyspepsia, flatulence, vomiting, melena, rectal hemorrhage, dry mouth, dysphagia, GI disorder, periodontal abscess, GI carcinoma
Common (1% to 10%): Increased liver enzyme test, alkaline phosphatase increased, elevated AST, elevated ALT, elevated bilirubin
Very common (10% or more): Nocturia (12%), hematuria (12%)
Common (1% to 10%): Urinary tract infection, gynecomastia, impotence, breast pain, urinary frequency, urinary retention, urinary impaired, urinary incontinence, decreased libido, dysuria, urinary urgency, hydronephrosis, urinary tract disorder
Common (1% to 10%): Anorexia, hyperglycemia, bone pain, myasthenia, edema, BUN Increased, creatinine increased, dehydration, gout, hypercholesteremia
Very common (10% or more): Anemia (11%)
Common (1% to 10%): Decreased hemoglobin, decreased white cell count
Postmarketing reports: Increased PT/INR due to interaction between coumarin anticoagulants and this drug; serious bleeding reported
Common (1% to 10%): Elevated creatinine
Very common (10% or more): Back pain (25%)
Common (1% to 10%): Paresthesia, neck pain, leg cramps, myalgia
Common (1% to 10%): Headache, neuropathy, hypertonia
Very common (10% or more): Dyspnea (13%)
Common (1% to 10%): Cough, pharyngitis, bronchitis, pneumonia, rhinitis
Uncommon (0.1% to 1%): Lung disorder, asthma, epistaxis, sinusitis
Postmarketing reports: Interstitial lung disease (sometimes fatal) including interstitial pneumonitis and pulmonary fibrosis, most often at doses greater than 50 mg
Common (1% to 10%): Rash, sweating, dry skin, alopecia, pruritus, herpes zoster, skin carcinoma, skin disorder
Postmarketing reports: Photosensitivity
Very common (10% or more): Infection (18%)
Common (1% to 10%): Influenza syndrome
Common (1% to 10%): Specified cataract
Common (1% to 10%): Insomnia, anxiety, depression, confusion, somnolence, nervousness
Common (1% to 10%): Neoplasm
Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.
Source: Drugs.com Casodex