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Generic Name: cetrorelix (injectable) (SE troe REL ix)
Brand Name: Cetrotide
Physician reviewed Cetrotide (injectable) (injectable) patient information - includes Cetrotide (injectable) description, dosage and directions.
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Drug Information:
Cetrotide is a man-made form of a protein that blocks the effects of certain hormones in the body that control ovulation (release of an egg from the ovary). If ovulation occurs too soon during fertility treatment, the eggs may not be suitable for fertilization. This medicine works by preventing eggs from being released too early (premature ovulation). Cetrotide is used to prevent premature ovulation during controlled ovarian stimulation. Cetrotide may also be used for purposes not listed in this medication guide. Learn more

Cetrotide Side Effects

Cetrotide Side Effects

Note: This document contains side effect information about cetrorelix. Some of the dosage forms listed on this page may not apply to the brand name Cetrotide.

For the Consumer

Applies to cetrorelix: subcutaneous powder for solution

Along with its needed effects, cetrorelix (the active ingredient contained in Cetrotide) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking cetrorelix:

Less common

  • Abdominal or stomach pain
  • continuing or severe nausea, vomiting or diarrhea
  • decreased amount of urine
  • feeling of indigestion
  • moderate to severe bloating
  • pelvic pain, severe
  • rapid weight gain
  • shortness of breath
  • swelling of lower legs

Some side effects of cetrorelix may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Headache
  • injection site bruising, itching, swelling, or redness
  • nausea

For Healthcare Professionals

Applies to cetrorelix: subcutaneous powder for injection


Common (1% to 10%): Mild to moderate ovarian hyperstimulation syndrome (OHSS) (WHO grade I or II)

Uncommon (0.1% to 1%): Severe ovarian hyperstimulation syndrome (WHO grade III)


Very common (10% or more): Nausea (12%)


The most commonly reported side effects were local injection site reactions such as erythema, swelling, and pruritus that were usually transient in nature and mild in intensity.


Uncommon (0.1% to 1%): Systemic allergic/pseudo-allergic reactions including life-threatening anaphylaxis


Common (1% to 10%): Redness, erythema, bruising, itching, swelling, pruritus (at the injection site)

Nervous system

Common (1% to 10%): Headache

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Cetrotide