Note: This document contains side effect information about pegaptanib ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Macugen.
Applies to pegaptanib ophthalmic: intraocular solution
Along with its needed effects, pegaptanib ophthalmic (the active ingredient contained in Macugen) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking pegaptanib ophthalmic:
Incidence not determined
Some side effects of pegaptanib ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Applies to pegaptanib ophthalmic: intravitreal solution
Very common (10% to 40%): Anterior chamber inflammation, blurred vision, cataract, conjunctival hemorrhage, corneal edema, eye discharge, eye irritation, eye pain, increased intraocular pressure, ocular discomfort, punctate keratitis, reduced visual acuity, visual disturbance, vitreous floaters, vitreous opacities
Common (1% to 10%): Blepharitis, conjunctivitis, photopsia, vitreous disorder, allergic conjunctivitis, conjunctival edema, corneal abrasion, corneal deposits, corneal epithelium disorder, endophthalmitis, eye inflammation, eye swelling, eyelid irritation, meibomianitis, mydriasis, periorbital hematoma, retinal edema, vitreous hemorrhage
Uncommon (0.1% to 1%): Retinal detachment, iatrogenic traumatic cataract, other adverse events related to the injection procedure
Very common (10% to 40%): Hypertension
Common (1% to 10%): Chest pain
Common (1% to 10%): Contact dermatitis, contusion
Common (1% to 10%): Diabetes mellitus
Common (1% to 10%): Diarrhea, nausea, dyspepsia, vomiting
Common (1% to 10%): Urinary tract infection, urinary retention
Common (1% to 10%): Arthritis, bone spur
Common (1% to 10%): Dizziness, headache, carotid artery occlusion, cerebrovascular accident, vertigo, transient ischemic attack
Common (1% to 10%): Hearing loss
Common (1% to 10%): Bronchitis, pleural effusion
Postmarketing reports: Angioedema and other anaphylaxis/anaphylactoid
Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.
Source: Drugs.com Macugen