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Generic Name: podofilox topical (poe DOF il lox)
Brand Name: Condylox
Physician reviewed podofilox topical patient information - includes podofilox topical description, dosage and directions.
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Drug Information:
Podofilox prevents the growth of certain types of cells. Podofilox topical (for the skin) is used to treat genital warts that appear on the outside of the body, but podofilox topical is not a cure for genital warts. Podofilox topical may also be used for purposes not listed in this medication guide. Do not use this medication on any warts or skin growths that have not been checked by your doctor. You should not use podofilox topical if you are allergic to it. Do not use podofilox topical on any warts or skin growths that have not been checked by your doctor. Learn more

Podofilox Side Effects

Podofilox topical Side Effects

For the Consumer

Applies to podofilox topical: topical gel/jelly, topical solution

Along with its needed effects, podofilox topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking podofilox topical:

More common

  • Bad odor (solution only)
  • bleeding of treated skin
  • blistering, crusting, or scabbing of treated skin
  • bloody urine (solution only)
  • burning feeling of treated skin
  • dizziness (solution only)
  • headache (gel only)
  • itching of treated skin
  • pain during sexual intercourse (solution only)
  • pain of treated skin
  • problems with foreskin of penis (solution only)
  • redness or swelling of treated skin
  • scarring of treated skin (solution only)
  • skin ulcers of treated skin
  • vomiting (solution only)

Symptoms of overdose

- in order of occurrence
  • Nausea
  • vomiting
  • diarrhea
  • chills
  • fever
  • sore throat
  • unusual bleeding or bruising
  • oral ulcers

Some side effects of podofilox topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Dryness of treated skin
  • peeling of treated skin
  • soreness or tenderness of treated skin
  • stinging or tingling of treated skin
  • trouble in sleeping (solution only)

Less common

  • Changes in color of treated skin (gel only)
  • skin rash (gel only)

For Healthcare Professionals

Applies to podofilox topical: topical gel, topical solution


Gastrointestinal side effects have included vomiting.


Local side effects have included burning, pain, inflammation, erosion, itching, and bleeding. Reports of burning and pain were greater and more severe in women than in men. Tenderness, chafing, malodor, scarring, vesicle formation, crusting edema, dryness, peeling, and ulceration have also been reported.


Genitourinary side effects have included pain with intercourse, foreskin irretraction, and hematuria.

Nervous system

Nervous system side effects have included headache, insomnia, and dizziness.

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Podofilox