Note: This document contains side effect information about rifapentine. Some of the dosage forms listed on this page may not apply to the brand name Priftin.
More frequent side effects include: diarrhea. See below for a comprehensive list of adverse effects.
Applies to rifapentine: oral tablet
Along with its needed effects, rifapentine (the active ingredient contained in Priftin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking rifapentine:
Some side effects of rifapentine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Applies to rifapentine: oral tablet
The most commonly reported side effects included anemia, lymphopenia, hemoptysis, and neutropenia.
Very common (10% or more): Anemia (up to 11.4%), lymphopenia (up to 10.5%)
Common (1% to 10%): Leukocytosis, lymphadenopathy, neutropenia, thrombocytopenia, thrombocytosis
Frequency not reported: Leukopenia, lymphocytosis
Common (1% to 10%): Abdominal pain, diarrhea, dyspepsia, nausea, vomiting
Frequency not reported: Clostridium difficile-associated diarrhea, constipation, dry mouth, esophageal irritation, esophagitis, gastritis, pancreatitis, salivary gland enlargement
Common (1% to 10%): Maculopapular rash, pruritus, rash, sweating increased
Uncommon (0.1% to 1%): Skin reaction
Frequency not reported: Facial edema, hyperhidrosis, itching, purpura, skin discoloration, sweats, urticaria
Common (1% to 10%): ALT increased, AST increased, hepatotoxicity
Uncommon (0.1% to 1%): Hepatitis
Frequency not reported: Alkaline phosphatase increased, bilirubinemia, hepatomegaly, jaundice
Common (1% to 10%): Coughing/cough, hemoptysis
Frequency not reported: Acute bronchospasm, asthma, bronchial hyperactivity, bronchospasm, dysphonia, dyspnea, epistaxis, laryngeal edema, laryngitis, oropharyngeal pain, pharyngitis, pneumonitis, pulmonary fibrosis, shortness of breath
Common (1% to 10%): Dizziness, headache
Frequency not reported: Convulsion, paresthesia, peripheral neuropathy, somnolence, syncope
Common (1% to 10%): Arthralgia, back pain
Frequency not reported: Arthritis, muscle pain, myalgia, myositis, rhabdomyolysis
Common (1% to 10%): Hypersensitivity/hypersensitivity reaction
Frequency not reported: Anaphylaxis, angioedema
Common (1% to 10%): Fever
Frequency not reported: Abortion, aches, asthenia, body fluid discoloration, chills, death, fatigue, feeling jittery, pyrexia, weakness
Common (1% to 10%): Anorexia
Frequency not reported: Decreased appetite, gout, hyperglycemia, hyperkalemia, hyperlipidemia, hyperuricemia, porphyria
Common (1% to 10%): Nonprotein nitrogen increased
Frequency not reported: Azotemia, blood urea nitrogen (BUN) increased
Common (1% to 10%): Conjunctivitis
Frequency not reported: Chest pain, flushing, hematoma, hypotension, orthostatic hypotension, palpitation, pericarditis, tachycardia, thrombosis
Frequency not reported: Anxiety, confusion, depression, disorientation, suicidal ideation
Frequency not reported: Hematuria, leukorrhea, vaginal hemorrhage, vaginitis, vulvovaginal candidiasis, vulvovaginal pruritus
Frequency not reported: Flu-like syndrome, fungal infection, viral infection
Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.
Source: Drugs.com Priftin