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Generic Name: diphtheria, pertussis acellular, polio, tetanus vaccine (dif THEER ee a, per TUS is a SEL yoo lar, POE lee oh, TET a nus)
Brand Name: Kinrix, Quadracel
Physician reviewed Quadracel patient information - includes Quadracel description, dosage and directions.
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Drug Information:
Diphtheria, pertussis acellular, polio, and tetanus are serious diseases caused by bacteria or virus. Diphtheria causes a thick coating in the nose, throat, and airway. It can lead to breathing problems, paralysis, heart failure, or death. Pertussis (whooping cough) causes coughing so severe that it interferes with eating, drinking, or breathing. These spells can last for weeks and can lead to pneumonia, seizures (convulsions), brain damage, and death. Polio affects the central nervous system and spinal cord. It can cause muscle weakness and paralysis. Polio is a life threatening condition because it can paralyze the muscles that help you breathe. Learn more

Quadracel Side Effects

Quadracel Side Effects

Note: This document contains side effect information about diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid. Some of the dosage forms listed on this page may not apply to the brand name Quadracel.

For the Consumer

Applies to diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid: intramuscular suspension

Along with its needed effects, diphtheria toxoid/pertussis, acellular/poliovirus vaccine, inactivated/tetanus toxoid may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking diphtheria toxoid/pertussis, acellular/poliovirus vaccine, inactivated/tetanus toxoid:


  • Abdominal or stomach pain
  • blurred vision
  • confusion
  • decreased urination
  • diarrhea
  • difficulty having a bowel movement (stool)
  • dizziness
  • dry mouth
  • fainting
  • fast heartbeat
  • fever
  • inability to speak
  • irritability
  • itching, pain, redness, swelling, tenderness, or warmth on the skin
  • lightheadedness
  • loss of appetite
  • muscle twitching
  • nausea
  • rapid breathing
  • restlessness
  • seizures
  • severe or sudden headache
  • slurred speech
  • sunken eyes
  • swelling of the feet or lower legs
  • temporary blindness
  • thirst
  • unusual tiredness or weakness
  • weakness
  • weakness in the arm and/or leg on one side of the body, sudden and severe
  • wrinkled skin

Incidence not known

  • Black, tarry stools
  • bleeding gums
  • blood in the urine or stools
  • bluish lips or skin
  • collapse or shock-like state
  • cough
  • difficulty swallowing
  • hives
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • pinpoint red spots on the skin
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • skin rash
  • slow breathing
  • swollen, painful, or tender lymph glands in neck, armpit, or groin
  • tightness in the chest
  • unusual bleeding or bruising

Some side effects of diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Loss of appetite
  • pain, redness, or swelling at the injection site
  • sleepiness

For Healthcare Professionals

Applies to diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid: intramuscular suspension


General side effects have included drowsiness, fever, and loss of appetite.


Hypersensitivity side effects have included anaphylactoid reactions, anaphylaxis, angioedema, and urticaria, apnea, collapse or shocklike state (hypotonic-hyporesponsive episode), convulsions (with or without fever), lymphadenopathy, and thrombocytopenia.


Local side effects have included pain, redness, swelling, and increase in arm circumference.


Gastrointestinal side effects have included gastroenteritis and dehydration.


Dermatologic side effects have included pruritus.

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Quadracel