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Symlinpen 120

Generic Name: pramlintide (PRAM lin tide)
Brand Name: SymlinPen 120, SymlinPen 60
Physician reviewed SymlinPen 120 patient information - includes SymlinPen 120 description, dosage and directions.
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Drug Information:
SymlinPen 120 is a man-made form of a hormone that occurs naturally in the body. This medicine lowers blood sugar in three ways. It slows the rate that food moves from your stomach to your intestines, which keeps your blood sugar from rising too fast. This medicine also lowers the amount of glucose (sugar) your liver produces. Lastly, this medicine triggers the feeling of fullness after meals to help control your appetite and decrease how much food you eat. SymlinPen 120 is used together with insulin to treat type 1 or type 2 diabetes. This medicine is usually given after other diabetes medicines have been tried without success. Learn more

Symlinpen 120 Side Effects

SymlinPen 120 Side Effects

Note: This document contains side effect information about pramlintide. Some of the dosage forms listed on this page may not apply to the brand name SymlinPen 120.

For the Consumer

Applies to pramlintide: subcutaneous solution


Subcutaneous route (Solution)

Severe hypoglycemia has occurred within 3 hours of pramlintide injection when used concomitantly with insulin, especially in patients with type 1 diabetes. Serious injuries may happen if hypoglycemia occurs during high-risk activities, and appropriate patient selection, instruction, and insulin dose reduction are critical for reducing this risk.

Along with its needed effects, pramlintide (the active ingredient contained in SymlinPen 120) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking pramlintide:

More common

  • Anxiety
  • blurred vision
  • chills
  • cold sweats
  • coma
  • confusion
  • cool pale skin
  • cough
  • depression
  • difficulty with swallowing
  • dizziness
  • fast heartbeat
  • headache
  • hives, itching, or skin rash
  • increased hunger
  • nausea
  • nightmares
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • seizures
  • shakiness
  • slurred speech
  • tightness in the chest
  • unusual tiredness or weakness

Some side effects of pramlintide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Difficulty with moving
  • inflicted injury
  • loss of appetite
  • muscle pain or stiffness
  • pain in the joints
  • stomach pain
  • vomiting
  • weight loss

Less common

  • Body aches or pain
  • congestion
  • dryness or soreness of the throat
  • fever
  • hoarseness
  • runny nose
  • tender, swollen glands in the neck
  • voice changes

For Healthcare Professionals

Applies to pramlintide: subcutaneous solution


Very common (10% or more): Severe hypoglycemia (up to 16.8%), anorexia (up to 17%)


Very common (10% or more): Nausea (up to 48%), vomiting (up to 11%)

Common (1% to 10%): Abdominal pain

Frequency not reported: Slower gastric emptying

Postmarketing reports: Pancreatitis


Common (1% to 10%): Allergic reaction

Nervous system

Very common (10% or more): Headache

Common (1% to 10%): Dizziness


Common (1% to 10%): Arthralgia


Common (1% to 10%): Cough, pharyngitis


The most commonly reported side effects were: nausea, vomiting, and severe hypoglycemia.


Postmarketing reports: Injection site reactions


Very common (10% or more): Inflicted injury (14%)

Common (1% to 10%): Fatigue

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Symlinpen 120