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Generic Name: varicella zoster immune globulin (VAR i SEL a ZOS ter im MUNE GLOB ue lin)
Brand Name: Varizig
Physician reviewed Varizig patient information - includes Varizig description, dosage and directions.
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Drug Information:
Varicella zoster (commonly known as chickenpox) is a common childhood disease that causes fever, skin rash, and a breakout of fluid-filled blisters on the skin. Chickenpox is usually mild, but it can be serious or even fatal in young infants, in adults, and in people who have a weak immune system. It can lead to severe skin infection, breathing problems, brain damage, or death. When varicella zoster virus becomes active again in an adult, it can cause herpes zoster (also called shingles) which causes painful blisters, skin infections, severe nerve pain, and hearing or vision problems that can last for months or years. Learn more

Varizig Side Effects

VariZIG Side Effects

Note: This document contains side effect information about varicella zoster immune globulin. Some of the dosage forms listed on this page may not apply to the brand name VariZIG.

For the Consumer

Applies to varicella zoster immune globulin: intramuscular solution

Along with its needed effects, varicella zoster immune globulin (the active ingredient contained in VariZIG) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking varicella zoster immune globulin:

Less common

  • Chills
  • nausea
  • rash
  • unusual tiredness or weakness

Incidence not known

  • Hives
  • itching
  • redness of the skin
  • shortness of breath
  • swelling of the eyelids, face, lips, hands, or feet

Some side effects of varicella zoster immune globulin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Headache
  • pain at the injection site

For Healthcare Professionals

Applies to varicella zoster immune globulin: intramuscular powder for injection, intramuscular solution


Local side effects have included pain, redness and swelling at the injection site.


Hypersensitivity side effects have included angioneurotic edema and anaphylactic shock in less than 1 in 1,000 patients.


General side effects have included headache, chills, back pain and syncope.


Gastrointestinal side effects have included nausea.


Dermatologic side effects have included rash.

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Varizig