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Generic Name: pitavastatin (pit AV a STAT in)
Brand Name: Livalo, Zypitamag
Physician reviewed Zypitamag patient information - includes Zypitamag description, dosage and directions.
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Drug Information:
Zypitamag is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood). Zypitamag is used to treat high cholesterol in adults. Lowering your cholesterol may help prevent heart disease and hardening of the arteries, conditions that can lead to heart attack, stroke, and vascular disease. Zypitamag may also be used for purposes not listed in this medication guide. Learn more

Zypitamag Side Effects

Zypitamag Side Effects

Note: This document contains side effect information about pitavastatin. Some of the dosage forms listed on this page may not apply to the brand name Zypitamag.

For the Consumer

Applies to pitavastatin: oral tablet

Along with its needed effects, pitavastatin (the active ingredient contained in Zypitamag) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking pitavastatin:

Less common

  • Difficulty with moving
  • joint pain
  • muscle aching or cramping
  • muscle pains or stiffness
  • pain in the arms and legs
  • swollen joints

Incidence not known

  • Chills
  • clay-colored stools
  • cough
  • dark urine
  • diarrhea
  • difficulty breathing
  • dizziness
  • fever
  • general feeling of discomfort or illness
  • headache
  • loss of appetite
  • muscle spasm
  • nausea
  • runny nose
  • shivering
  • sore throat
  • stomach pain
  • sweating
  • trouble sleeping
  • unusual tiredness or weakness
  • vomiting
  • vomiting of blood
  • yellow eyes or skin

Some side effects of pitavastatin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Back pain
  • difficulty having a bowel movement

Incidence not known

  • Burning, numbness, tingling, or painful sensations
  • decreased interest in sexual intercourse
  • discouragement
  • feeling sad or empty
  • hives or welts, itching skin, or rash
  • inability to have or keep an erection
  • irritability
  • loss in sexual ability, desire, drive, or performance
  • loss of interest or pleasure
  • loss of memory
  • problems with memory
  • redness of the skin
  • trouble concentrating
  • unsteadiness or awkwardness
  • weakness in the arms, hands, legs, or feet

For Healthcare Professionals

Applies to pitavastatin: oral tablet


The most frequently reported side effects have included myalgia, back pain, diarrhea, constipation, and extremity pain.


Common (1% to 10%): Constipation, diarrhea

Postmarketing reports: Abdominal discomfort, abdominal pain, dyspepsia, nausea


Common (1% to 10%): Back pain, myalgia, pain in extremity

Frequency not reported: Arthralgia, rhabdomyolysis, myopathy, myositis, elevated creatinine phosphokinase

Postmarketing reports: Muscle spasm


Frequency not reported: Bilirubin increased, liver enzymes abnormal, elevated transaminases, elevated alkaline phosphatase

Postmarketing reports: Hepatitis, jaundice, fatal hepatic failure, nonfatal hepatic failure


Frequency not reported: Rash, pruritus, urticaria


Frequency not reported: Influenza, creatine phosphokinase increased, transaminases increased, alkaline phosphatase increased

Postmarketing reports: Asthenia, fatigue, malaise

Nervous system

Frequency not reported: Headache

Postmarketing reports: Dizziness, hypoesthesia, peripheral neuropathy


Frequency not reported: HbA1c elevations, fasting serum glucose elevations, increased blood glucose


Frequency not reported: Acute renal failure, myoglobinuria


Frequency not reported: Nasopharyngitis

Postmarketing reports: Interstitial lung disease


Frequency not reported: Hypersensitivity reactions including rash, pruritus, and urticaria


There have been reports of cognitive impairment such as memory loss, forgetfulness, amnesia, memory impairment, and confusion associated with statin use. These reports are generally nonserious, and reversible with drug discontinuation. Time to symptom onset has been reported as 1 day to years with resolution at a median of 3 weeks following discontinuation.

Postmarketing reports: Insomnia, depression

Statin use:

Postmarketing report: Confusion, cognitive impairment, memory loss, forgetfulness, amnesia, memory impairment


Postmarketing reports: Erectile dysfunction


Statin use:

Postmarketing reports: Immune-mediated necrotizing myopathy

Editorial References and Review

Medically reviewed by BestRx Medical Team Last updated on 1/1/2020.

Source: Drugs.com Zypitamag